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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc41003ba3dac9c29b25ecf4c69d453de0d2f7e433fb3fce65314ebb8245ab5' 
  AND token = 'tNYx9A/CHycEqpc4hGX6xw2yxFvQzupZsG5tn7G6xgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}