SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '488ffc201ed09e8fbaa8cfc08916f2606578d35e042cc379ce78054809d538f3' 
  AND token = 'BpBbZeDVzzq/6PwC1rlbo+3O/K2mjprTR5ZtorQ4Kd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}