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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6b4aad3e06dd3ad53c1d2d1a949ec2dee1fba807ec58a201b62702c6449567' 
  AND token = 'PIRZRowDbOR/DspoJ+/nEpiljNJ6agCPPCeOpRNtVhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}