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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af345946c90874c43e3d7cd3b5194e455ffcf254aefce31e7522cc1ab83e74e9' 
  AND token = 'dkgCXAxHw1lgxJ+R5cGMKxjLhdA0acnit+R0yQ6iMqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}