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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755ad69e0d3086ef102e654be4dc6c8ff1b89fb44c8e503823dfd2dfa33ebf8d' 
  AND token = '68DFyT6ex/aKTrNFRLpJXFo6Rw50xh5JJhFg2Pv/lZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}