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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e52e1b780791fe0ded273b440d1f5d2ce035cccbeed1ce781a01d9c26c844a' 
  AND token = 'ar7+DoNdCN0ossFhAkzC43ct4dzRPnT0kzRggpXVlIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}