SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e02a6ef8db27c3fd0a9bc295dd46813d853edf9f65db709cda4a4bc3592c0ed1' 
  AND token = '4HAoxrwpz+3dQBZdpVI231Cx1u/PRNxYeHC0HTre1QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}