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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de86d266fa3915358017e1b7a01f1d8e5c394d8635c3b66c8a228b78c1791348' 
  AND token = 'SSmXo4ckN4+EdPu9xh6T/2gHpqGyUrA9bqV9lRdRmMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}