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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3879c0f22e533447e16006abfd382fa840381aa16066a50a332cd46b4a31db1f' 
  AND token = 'vpiqTJpBMr51Emk+RAGvbIcNVBMWxceUvEr9S+1wDeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}