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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a03cdc9d1053349d18ef648f33b1dc7800edf55305f41319ee6c250dd729b8da' 
  AND token = '+0a3NkIHgMkG5mWS7mkYtjTp5ntvGx1I7jPeaW0yTHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}