SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6e65eb9729dc363ef85b3abf2f3e69d25493e6d8f204a5366ddfd22531f0ca9' 
  AND token = 'c8LepT6N1C2JriGJFGa5c5JYLdLyEYz0S9nHxEaotf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}