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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffad9443322e1621020411995473d63bf0233459e0560aab8a617cc389322e3c' 
  AND token = 'rnO0MypyFxu0il/HiK8RmIgB8oWL+f3X6XbEcQaLlsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}