SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9681ed949f4c71021fd5bebc9d875733f377d7aba58491183289bc491ec8454c' 
  AND token = 'rT2FGXgpASaShIhLScrudURJvOGGeGR8D9DQcmZtKy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}