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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38ded912ae32c7da7210d3f1b6d94473c4c5c3fcd91953cdea1d782774cddddb' 
  AND token = 'clECWPLbEVYXYdNs+pvfRMt6Ep+IiSDK7eIXc9rjd0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}