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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fe4971d4697b764109bd64986b8b3754b8b1bfaf637affbabe467644b8b0300' 
  AND token = '1cszCY0OrDwjeUeleyt4pdmc1LNP3/TMFV8yZ9xESto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}