SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb0edad55e2eeabbe277d34968fe6de7f735a050e7e66ae10829f193c0ab2af' 
  AND token = 'ceQi70uV1I2gONjyHsCfxPTrYKUdfkjBUT+57uW9HVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}