SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8144d8408d9dd1611b0b11aefa9786ed7ff3d2050b956abff0683fd28f3a10ce' 
  AND token = 'prdZ7rQz2Vq8HFVzjsiVDPsfF4mrqmIg/WlZnsKmcAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}