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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d81fd34b15b6dd726d1d75e6293316078e8681fa7a7c2a338d200d8d9f768d0' 
  AND token = 'U4arnnxSrIarXXmUO8jMniqWl/B+Y41QC7P7rdPxcR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}