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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db120f1b5b37e632b6a2b68a99d271c66b0c4fd59176acb3c5a3a8db6a62391' 
  AND token = 'qZt2G/yC/G1q2oeL8hqyAv9qA1dUcUvuX+bJgKtdfDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}