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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e99e8e92a624de317f4f973f66f8ac4d6c4965499704020a18c44a0015fec8fa' 
  AND token = 'Eik0Z4zc+PuDRtsKJYtnUMFC5GT9O5qgcwlpLl+O5Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}