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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e8c94650f6b14644774d68ee284e4a4d16a348ab0a09f2a9acdfb3d094a07c8' 
  AND token = 'PRFds9JZoYogSY7UracxYwu7R2L7zXfdWyANiR9OZEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}