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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4449365ba05d91541c66bb487f0da6492214b838591461732bd926816c63794' 
  AND token = 'DjkgxodIV1mQxbnx08Bfs0VJ2EZmS37y60Qba+lXKO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}