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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9849fef0009c41779e41f159c083a2aaf4224b94fe10f55806da7ffa60589e38' 
  AND token = 'dKkNy+/ShzrGg/4U/b4GGixGG8YNhG0fjOx9Z+RYqxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}