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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2543d1dab2888aa11d3bad96150c5285b2abf387bdfe74c5e58a47cc502aff8' 
  AND token = 'hCZtaD8ZFo1rKlG2aaNA5RqeL+GpN/hPQWD/QQm9FOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}