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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43068bae3456b83b9aab82b4eaaa221c0fd7454023b0c85474be028b5f3d7dc9' 
  AND token = 'UTFdZE1PPo3bz6INPkof24BCGzWHftKOT/T9Lcw+8fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}