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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a281d20e2292ac9d99d0016aa071a2ac9b060f231ca158fa338c3c5dd447f33' 
  AND token = 'f7xh5HK5rQofqQUXlMS+yC2RaS2EtyafuGw/8xTh7bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}