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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185300d2842e5869ba87d6da0c0ee88b9b953a0b50f796c87327ee01011b3990' 
  AND token = '4tvjnSO7Eczx53L8jvpcfwW6qidQOixfNckygz/GJ4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}