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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cc6af6838e6adc5ef36914216c907bd1af9af0b8b1f9c1c6311777a36c87ec2' 
  AND token = 'ECr9JAaDOXF8T9UFZy0R/prONCBQQD7Bg5Ab78BMD1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}