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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1395d8aec6a42ca7e3c3ce3bde290da02d18673e4c89971a64ff80e0672f1168' 
  AND token = 'uBSCXVdmwNV59LWfVz7RDCaTqG87HTfEXhIsN9mIHd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}