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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17feb8d5173b1349b9485e14e65b8b40d76273e2328d66f2a638a752b199a696' 
  AND token = 'EPWPZdgAw2gxSE8snJtrIIrMGFYFayfbPoyl9RE76ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}