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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af334cc886560a374e55a2a8b413c00ca13436e1e8fc129cf1da4287a4de2864' 
  AND token = 'EgkijINg8pgg+jB4doT5UBzrzrvFRl5H2vLvaqNmpLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}