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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ee2eb62bf01e884311cf5c784e91178d6b243151c2f32f83af235a19e9df6c5' 
  AND token = '4x3odS0RmyXGQE5YaXdxt5UOeBaztu7JHEjaiOAXtYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}