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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aba729436661126a04c8e79ef71d94088ffc972c75bef929103768bf28e13ad' 
  AND token = '2ey9gDfim/A0QiYz8HmgZLREA+XnJd1OW8G/W+0fo5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}