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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dd783e67601e714e14d96931196997e86e7d824ac68321515c7c7669cd936f6' 
  AND token = '1j4y6SdgHzEsAiqaA3qZ0GPP/ryqZu5T5NXhGXZHoDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}