SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7dbedf1d6517d756e4d34c6fef41fcc4e6ea3404cfb5ac1677283ba2c838475' 
  AND token = 'Iv4yAyiaUIOAVQ28hO+YCPphCR4SYrvFfOxP7tM8mpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}