SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46731626eb85161fbfc94ce5a5e27b42918df5c4198ad6110b22b4f2731fc741' 
  AND token = 'VAJcLkbTx6/nw9vB6MfB8CosYkUUVivAD7pHHKGfOdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}