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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23b2c5bb7a38143dfb51cea9561fce5c8c31ecf23df274a06d4708490a872430' 
  AND token = 'IuPWUfQCJE5Mw00/8A2NQEIFuMuUPHQt4BEionW0GK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}