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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '279956fd8721c50481a5faa9f68614910d3c1b0d6a763ced5564adeedf35a848' 
  AND token = '2sAv6VifNrHerr5TQMs2oGS5P1UxKcAjKiwzA/Jjog4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}