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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59f4e178cc28077939d5f414b7f47c05d7b3fc2c457b530b0d55c7ec23038dbf' 
  AND token = 'RAou/Guaf02D3huvyj55CRotnUMxMR485gB/TDcQZbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}