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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66624ed6fa953f0369acfc6bb4359f5482ab505289d34b865de61b1bb125f1c2' 
  AND token = 'WCL+EEfr1dJhs0jVqfAZbdfI4GhoN2iRVDYE8xOv3QM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}