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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52955bd0af90ca3e9ddb2edb79a5fce6a17b2a131dba4309455447e81abfb80e' 
  AND token = 'Kl0WBA0l6lJFD0fSAMDzEKPNRX3273oIEQGfrd8GbIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}