SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7a993c148a8e6bd3dbc1375335e581544b410d3b475dbdcf46e5c29392019c' 
  AND token = 'mwhzt3vqa2rGl072/0rhi+PrVLd5OK0fzJjoendcjjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}