SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050ccd5dcda45b097ab8ed72ee3997ca880be1d865898a65d3df22a41ef261ad' 
  AND token = 'oZYz3mELa5uCBPJ2b8P9s3O06sbQwdtmSk82Y0ryskU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}