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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bf8d9401dcc1672dcf71dd7cff6a9030653feda327a2f48e62af5a38eea8d83' 
  AND token = 'bJ/kEO/LmVIBGO4DU/e1hJ9FWTwLlU6d1S46/39alsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}