SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0740b02d00c8ece3dd3184193375c00af95f033560d83e26cd9325079d3af2ee' 
  AND token = 'uWQyJ/Al0ORn/SwOYMqd1UrPHHes1sRdmQK81dcFMqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}