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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33f5acec7725e775ddce978ce36d237504eb2375057699a77eed6b0cc7f0158' 
  AND token = 'PSSP/LbC0ZohHOd7DkSLW/5/2COHPhMJAFiuDmu4Ll8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}