SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b6eb674050965e5fb250e67d6d38de752812fb9eecea0c5f6e4fdb4a0bd8af2' 
  AND token = 'hePkVO+JC3O4qQ+NuGhKhqzqkd19NCRvBmm9PUo+A60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}