SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c67550144287d08f28b6084d0c73840c2dc3ec4e2b54ee9af1a485816e59bb10' 
  AND token = 'PaiBWuRWsqFiVlae7uEsfd8g79XalIYodDPR713yMdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}