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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66b303199c9dce07ae57d1a43c66501bbeb35714764d144d4e0e7ae61563f5f0' 
  AND token = 'clJJIJmqSk32YHy8hFiLtnlAO6zkx5UhH2Gzhk2y0s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}