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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c6b995380c63ee7adc41100e4baf9f2ff42c73d6d9c20bd6db2a6bf55adc10' 
  AND token = 'RqsTWjf3zokCAuW/6N220LpRjNUfCW6Irx0mdy3bSY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}